Orthobiologics Myths vs. Facts: What 2026 Research Really Shows
If you've spent any time around an orthopedic clinic, a sports medicine forum, or a wellness ad lately, you've probably heard the pitch: platelet-rich plasma (PRP), stem cells, and exosomes are being sold as everything from a way to dodge knee replacement to a full-on cartilage regrow button. At the same time, skeptics dismiss the whole field as expensive saline with good marketing. Neither extreme lines up with what the actual 2025-2026 research shows. A wave of new meta-analyses, a contentious Lancet review, and a fresh round of FDA warning letters have all landed in the past year, and together they paint a more interesting - and more useful - picture. Here is what the current evidence actually says about the most common orthobiologics myths. What Exactly Are Orthobiologics? Orthobiologics is the umbrella term for substances derived from a patient's own body - blood, bone marrow, or fat tissue - that are processed and re-injected to try to calm inflammation and suppo...